Thesis Nootropics Review (aka Formula): Are Personalized Nootropics Worth it?

Medically reviewed by Dr. Steve Kim, MD

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Nootropics have always been this kind of vague, mysterious area in the health and wellness world. I mean, there’s definitely no shortage of brands out there offering their own “brain health” supplements, promising improved cognition, memory, and focus. Because at the end of the day, that’s an extremely compelling benefit.

But at the end of the day, because nutrition supplements aren’t regulated by the FDA, these claims aren’t lab-tested to the same standards that say, prescription medications are. Those are exactly the reasons why we went so deep into our initial research: Are Nootropics legit? Or is it just marketing hype? We found out.

…aaand then we went even deeper with our analysis on the Best Nootropics for ADHD. 🥵 but rest assured, you’re in the right place now. 

Here are the three key points that we got from that research:

  1. Not every ingredient that’s on a nootropic label is actually proven to have significant cognitive benefits.
  2. There’s a LOT of marketing BS out there in the nootropics space. And price does not necessarily correlate to improved efficacy.
  3. What works well for me won’t necessarily work well for you, your sister, or your friend.

With that being said, our team has tested several of the most popular nootropic brands out there today. And not to ruin the surprise, but Thesis is at the top of our list. We’ve also got a 10% coupon code for Zenmaster readers. 🙂

Let’s get into it.

Who is

Thesis nootropics product shot
One of each blend that I received in my Starter Kit

The first time I heard of Thesis was actually from an Instagram ad. (Not sure if I had been Googling around for nootropic brands, or if Siri was eavesdropping on my conversations with friends, but that’s besides the point.)

Formerly known as, it turns out that Thesis has been around for years; they’re not just some newcomer to the space. And they’ve got the history to prove it. With over 500,000 customers over the years, they’ve built up a data set of nootropics research that’s so incredibly dense, Thesis says it’s the largest in the world. 

And where does that data come from, exactly? 

Well, when you sign up for Thesis, they walk you through a fairly short questionnaire that’s designed to learn about you. Then it runs your responses through their algorithm to match you up with the nootropic blends that are the most likely to work best for you. Test those for a month, decide which one you like the best, and that purchase data goes right back into making the algorithm stronger.

So you can imagine that 500,000 customers later, it’s pretty damn reliable, which means their team is even more capable of offering up the perfect blend for new customers.

How’s that for big brain? 🧠

How does Thesis work?

First off, you’ll want to jump on Thesis’ website and start filling out that questionnaire. It’s all basic stuff and doesn’t require any in-depth medical records or anything.

Once you’re done with the survey, Thesis’ algorithm will run through its millions of datapoints to predict which four (out of five) blends have the highest probability of improving your life. Check out (using code ZENMASTER for 10% off 😉 ) and wait.

When you open up the package, you’ll find four blends. For me, they were Clarity, Creativity, Logic, and Energy. Basically, you’ll take one blend for six days, taking note of how it feels in the little daily journal that they include in the starter kit.

Opening up my Thesis starter kit
Opening up my Thesis starter kit

Throughout your week taking Creativity, how’d you feel? More productive? Better focus, or less procrastination? Energized? Great. Whatever it is, make note of that. The next week, you’ll repeat it with the second blend, and so on.

You’ll also have the ability to hit up their coaches at any time. I did, just to talk about the fascinating world of nootropics, and had an amazing convo with one of their neurologists, Cindy. It was just one of those awesomely genuine conversations that sometimes life spoils you with. I also learned that all their coaches have a strong background in the health industry: whether they’re neurologists, doctors, pre-med CPTs, etc.


By the end of the month, you should be able to pinpoint which blends (usually two) worked best for you. Remember that they’re unique in their own ways, so you’re basically picking which tools you liked best from the Thesis toolkit. Don’t feel like you have to pick just one. 

The whole process is actually a super smart approach to developing nootropics. Because at the end of the day, each blend is pretty radically different — just like our brains. It feels like one of those ideas that’s a total no-brainer.

How does Thesis compare to the best nootropic brands?

You know that saying, “Jack of all trades, but master of none”? That’s most nootropics on the market. Brands do a good job of researching all the most effective, research-backed ingredients — things that improve focus, mental clarity, energy, etc — and then they’ll jam it all together in a pill.

Buuut… that’s not necessarily the smartest move, if you think about it. I mean in theory, some of the benefits could counteract each other, or prevent you from actually achieving the desired effects.

If you’re looking for a nootropic to give you a lot of energy and motivation, but you also want something to calm you down and allow your mind to achieve clarity, how could a one-size-fits-all pill do that? You need to get more granular. 

So Thesis takes this other approach of going, “Okay, we coooullld stuff a bunch of effective stuff in one pill, or we could create these different ‘silos’ of mental benefits, and create a unique concoction for each one.”

And that’s exactly what they’ve done. And they’ve done it very well. But before we get into why our team loves that approach so much, we’ve created this comparison table to pit Thesis up against Onnit and Plato, two of the most popular nootropic brands.

Comparison table: Thesis vs Onnit Alpha Brain vs Plato

Thesis logo Onnit logo Plato logo
Customer rating4.5 ✩ (7,411 ratings)4.4 ✩ (18,302 ratings)4.6 ✩ (54 ratings)
Starting Price$119$80$46
Price (Subscribe n Save)$79$68 (only avail. directly from Onnit)$31
Price per day (full dosage)$3.29$1.51$1.03
Coupon codeZENMASTER for 10% offZEN10 for 10% off
Customized formulas
Access to coaching
Sample packs available?$7 for one week's worth
Refund policy?30 days90 days30 days
Caffeine Free?✔ (optional)
List ingredients and amounts ?
Legit, research-proven ingredients?✔ (but they're unclear about how much )

My personal review of Thesis nootropics

Short answer: I’ve been loving Thesis since I started using it almost four weeks ago (and yeah, I know it’s almost time to restock). 

But before I can get into all the whys, I (quickly) want to preface my review with a little background reminder on the world of nootropics. I promise it ties into all this.

Nootropics are a complex little corner of the vitamins & supplement industry. While drugs like Advil will pretty universally help to ease headaches for most people, vitamins  won’t necessarily have the same degree of efficacy in everyone.

Let’s take a quick sec to think about how these nootropics blends are made. Researchers sift through all the available studies and anecdotal reports in an effort to find which naturally occurring substances seem to be the best at improving cognitive function. Then they’ll take note of the dosages required for each, decide which ones make most sense to include in the formula, find the most common denominators, and…

BOOM! 💥 They’ve got a blend that they hope will work for most people – according to the data.

The problem is: that’s a one-size-fits-all approach. It’s a shotgun approach that tries to do everything at once, but at a certain point, the effects all kind of blur together (and maybe even detract from one another). 

Thesis says nah.

Why personalized nootropics are awesome

Other nootropics are trying to be a Swiss Army knife. They’re packing a bunch of different stuff into a couple pills and calling it a day. And while they do include good stuff in there that does work, it’s not necessarily the best approach (in my opinion).

Thesis clearly agrees with me. Because what they’re offering is a complete tool kit. They’re giving you four different tools – a Hammer, a Screwdriver, a Drill, and a Level. They’re saying, “Hey, each of these was uniquely built for specific purposes. And they do each thing very well. But don’t try to use this Level to nail stuff into the wall. Use this Hammer instead.” 

It is so insanely clutch.

Does Thesis' nootropics work?

While there’s no nootropic in the world that’ll give you some “brain blast” feeling like you’d get from Adderall or intense medications, but in our team’s experience, yes – Thesis nootropics work surprisingly well.

And by “surprisingly well”, I mean they offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out. I’m able to sit down and work, without feeling like I’m just hopped up on too much caffeine or whatever. 

And in the world of nootropics, where some brands don’t seem noticeable at all, it cannot be overstated just how awesome these effects have been.

Anyway, that’s just been my personal experience. In a sec I’ll share some reviews I found on Reddit and FB. But first:

Are Thesis nootropics legit?

✅ Pros

  • Thesis customizes your blends so that you’re taking specifically what’s best for your brain (and you’re not paying for what your brain doesn’t want).
  • They offer personal coaching and support by their team of nootropics coaches (dietitians). 
  • Choose between five different formulas to really hone in on which elements work best for your brain: Motivation, Creativity, Logic, Energy, and Clarity. Supposedly there’s another coming out in Feb 2022.
  • No proprietary blends. Thesis clearly publishes not only which ingredients they include, but also the exact amounts of each ingredient. Why does this matter? Well this way, teams like ours are able to actually cross-check that the dosages in Thesis match up with the ones from the clinical studies where benefits have been proven. It’s seems like a no-brainer, but this is sadly a rarity in the supplements space. And Thesis is also knowingly exposing themselves to the risk that customers will just buy individual ingredients in bulk and dose things out themselves to save a few bucks.
  • Choose between caffeinated formulas or caffeine-free ones. They don’t just load their nootropics up with caffeine to trick you into *thinking* your brain is working better.
  • They work (in our experience). Over a month of testing (6 days per week) showed that Thesis delivers on their promise of increased cognitive benefits.

❌ Cons

  • They don’t offer a free trial, like Onnit does. They do, however, offer a no-questions-asked refund.
  • The price tag. Even with the Subscribe & Save option, you’re looking at spending $80/mo. So they’re definitely one of the pricier nootropics on the market. Two things to note:
    • Use code ZENMASTER for 10% off. It’s the same % discount as you’ll find on coupon sites / browser plugins.
    • IMO, you may as well choose the Subscribe & Save option, even if you’re not sure about them. Why? Because you can just cancel your subscription before next month’s shipment arrives.

Thesis nootropic reviews: What are other customers saying?

Average Rating: 4.5 stars (of 7,411 reviews)

The customer rating above is taken from Thesis’ website, which I don’t usually love showcasing as the most trustworthy source of social credibility…  BUT searching through Reddit and Facebook, things still look great. A lot of folks highlight the same things I’ve shared here.

It seems like I’m not alone in my sentiments on Thesis. Take a look at some that I think do a particularly good job of portraying the overall vibe I got from my research. 

tldr; Are Thesis nootropics worth it?

I’m happy to report that this is one of those exciting times when our team discovers a company that’s bringing something truly unique to the market. At first glance it may not seem like it (just another personalized vitamin, right?) but in practice, this model works SO damn well. Just fill out that short survey on their website (which again, uses a truly massive data set), give each of the four blends a shot, take note of which have the most positive effect on your life, and you’re off to the races. 

The #1 thing I learned when I started using Thesis is that what they’re really offering is a complete toolkit of nootropics. I mean, I’ve always known that not all nootropics are the same (or even all that similar), but this approach of offering unique blends for different uses is just infinitely better than traditional nootropics that take a shotgun approach. It just works. 

I’ll never tell anyone how to spend his or her money. But what I am comfortable saying is that if you’re at all intrigued by Thesis – whether you’re completely new to nootropics, or you’ve been around the block – it’s absolutely worth giving their starter kit a shot. At $79 (or around $70 with code ZENMASTER), it certainly ain’t cheap. But I’m fully on the Thesis train.